2010 - present

  • Capillary Electrophoresis – a part of iConsensus, an integrated control and sensing platform for biopharmaceutical cultivation processes
  • Method puberty; adenovirus quantification CZE method implementation challenges
  • The development of a bromide quantification method for viral vaccine development
  • The implementation of a new method development process
  • A multipurpose adenovirus CZE method
  • Quality Methods by Design
  • Novel CZE Method for the Quantification of Intact Adenovirus Particles – AQbD Implementation and Application
  • Influenza virus proteins CGE method development; the effects of the injection mode and gel buffer dilution
  • Toward robust analysis of human growth hormone by capillary electrophoresis-mass spectrometry - essential considerations
  • Implementation of capillary electrophoresis for viral vacine development support in a GMP environment
  • Novel CZE method for the quantification if intact virus particles in complec matrices - Quality by Design method development
  • Enriching the analytical toolbox for viral vaccines with capillary electrophoresis
  • Improved method for quantification of virus particles in complex matrices using capillary electrophoresis
  • Novel method for the quantification of adenovirus particles in complex matrices using capillary zone electrophoresis
  • How to access the performance of capillary electrophoresis instruments
  • Capillary Electrophoresis: an Attractive Technique for Chiral Separations
  • Capillary Gel Electrophoresis for Analysis of Polio Virus - Development and Qualification in 4 Days
  • In-Capillary sample concentration in CE – “This is my analyte, how do I stack?”
  • Capillary Gel Electrophoresis for Analysis of Influenza Virus – The effects of injection mode and gel buffer dilution
  • QbD and CE: some practical points for attention
  • Quality by Design and Good Working Practices for CE
  • Capillary Gel Electrophoresis for Analysis of Influenza Virus – Development of an orthogonal method for influenza identity and HA quantification
  • Viral vaccine characterization with capillary electrophoresis
  • 50 Ways to improve your CE method
  • Comparison of chiral NACE with CD-MEKC using a chiral acid as model compound

2000 - 2010

  • Microemulsion electrokinetic chromatography: Investigation of the applicability on Solvay drug products
  • Quality by Design: Multi-factorial optimization of a CD-MEKC method for the chiral separation of an acidic drug substance and its formulations
  • Development and validation of the chiral separation of an acidic pharmaceutical compound and its enantiomer with CD-MEKC
  • Development of a dissolution method for in vitro-in vivo correlation of BCS class I and II drugs
  • Towards precise and validated bioanalysis – CE‑MS, protein adsorption, HPLC assays
  • Enantiomeric purity determination of Adrenaline at low concentrations in Local Anaesthetic solutions
  • Long term precision in capillary electrophoresis electrospray mass-spectrometry
  • Long term system testing of precision using a capillary electrophoresis electrospray mass-spectrometry standard method
  • Microemulsion electrokinetic chromatography of drugs varying in charge and hydrophobicity. Impact of parameters on separation performance evaluated by multiple linear levofolinate including related substances using statistical experimental design regression models
  • Development of a robust chiral capillary electrophoresis method for calcium
  • Separation of dipeptide and tripeptide enantiomers in capillary electrophoresis using cyclodextrins
  • EOF variations caused by the volatility of buffer components: diagnosis and therapy

1993 - 1999

  • Enantiomeric separation of underivatised dipeptides with capillary electrophoresis II. Alanyl and leucyl dipeptides
  • Enantiomeric separation of underivatised dipeptides with capillary electrophoresis I. Glycyl dipeptides
  • Extension of the model for chiral separations in capillary electrophoresis
  • Determination of bromide in a local anaesthetic drug by capillary electrophoresis using direct UV-detection and acetonitril for improvement of the selectivity of the method
  • Comparison of  Capillary Electrophoresis with Liquid Chromatography for the Enantiomeric Purity Determination of Ropivacaine Hydrochloride - Extended method comparison: introduction of the CE technique for routine analysis
  • Extension of the model for chiral CE by complex formation of one enantiomer molecule with more than one chiral selector molecule
  • Enantiomeric separation of a tetrapeptide - Extension of the theoretical model for chiral separations in capillary electrophoresis
  • Robust methods in Capillary Electrophoresis - Robustness of a method for determination of the enantiomeric purity of ropivacaine hydrochloride in pharmaceutical formulations
  • Comparison of CE with LC in the enantiomeric purity determination of ropivacaine
  • Chiral separation of local anaesthetics with capillary electrophoresis - Evaluation of the inclusion complex
  • Validation of the CE method for the enantiomeric purity testing of ropivacaine
  • The enantiomeric separation of local anaesthetics with capillary electrophoresis
  • Capillary liquid separation techniques coupled to flame-based gas chromatographic detectors
  • Improved interface for the coupling of capillary liquid separation techniques to flame-based gas chromatographic detectors